April 3, 2015

The study of peripheral blood erythrocytes using two-photon microscopy

The research group from the Institute of Molecular Biology (National Academy of Sciences of RA) successfully demonstrated the use of Eosin as a fluorescent dye to image the peripheral blood erythrocytes using two-photon microscopy at the DELTA laboratory. Eosin has excitation/emission wavelength of 521/544 nm, respectively. For two-photon microscopy these wavelengths fit well with the AREAL laser wavelength of 1030 nm.
The work is performed in the framework of the project “The study of the anti-aging compounds”. The aim of this project is to study the potential protective effects of new harmless and effective compounds against aging at the cellular level. Oxidative stress plays a pivotal role in aging processes. In order to suppress oxidative stress, synthetic antioxidants are often used, that violate cells’ natural metabolism. Therefore, the study of natural compounds protecting against oxidative stress is currently considered especially important.