February 20, 2020

Radiobiological Research at AREAL

The Russian Science Foundation has approved the second stage of international research project “Molecular and Cellular Effects of Ultrashort Pulsed Radiation” headed by Prof. Andreyan Osipov from N. N. Semenov Institute of Chemical Physics of Russian Academy of Sciences. The project is conducted within a close cooperation of N.N. Semenov Institute of Chemical Physics, Moscow Institute of Physics and Technology, A.I. Burnazyan Federal Medical Biophysical Center (Russia) and Yerevan State University, Institute of Molecular Biology, CANDLE SRI (Armenia).

The electron irradiation experiments are conducted using 3-5 MeV energy ultrashort electron pulses of laser driven AREAL facility at CANDLE SRI. This type of accelerators provide a unique opportunity to investigate the effects of ultra-short pulsed electron beam irradiation with the energy in MeV domain at different dose rates, providing sufficient beam stability, reproducibility and reliability for radiobiological experiments.

The first experimental results obtained on AREAL facility were published in the October issue of the International Journal of Molecular Sciences (N. Babayan, et al., “Laser-Driven Ultrashort Pulsed Electron Beam Radiation at Doses of 0.5 and 1.0 Gy Induces Apoptosis in Human Fibroblasts”, Int. J. Mol. Sci., 20, 5140, 2019).